diff --git a/Cargo.lock b/Cargo.lock
index be667f8883d8..f716ba850e4c 100644
--- a/Cargo.lock
+++ b/Cargo.lock
@@ -2869,6 +2869,12 @@ dependencies = [
  "proc-macro2",
 ]
 
+[[package]]
+name = "r-efi"
+version = "6.0.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "f8dcc9c7d52a811697d2151c701e0d08956f92b0e24136cf4cf27b57a6a0d9bf"
+
 [[package]]
 name = "rand"
 version = "0.8.5"
@@ -3087,12 +3093,12 @@ dependencies = [
 [[package]]
 name = "region"
 version = "3.0.2"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "e6b6ebd13bc009aef9cd476c1310d49ac354d36e240cf1bd753290f3dc7199a7"
+source = "git+https://github.com/RossComputerGuy/region-rs?branch=fix%2Fuefi#8f86bd4cd9951e61c20b9c2ed1048fd3f5e5955f"
 dependencies = [
  "bitflags 1.3.2",
  "libc",
  "mach2",
+ "r-efi",
  "windows-sys 0.52.0",
 ]
 
diff --git a/cranelift/jit/Cargo.toml b/cranelift/jit/Cargo.toml
index 4fc6e79a2d37..8e0124fcbd59 100644
--- a/cranelift/jit/Cargo.toml
+++ b/cranelift/jit/Cargo.toml
@@ -21,7 +21,7 @@ cranelift-entity = { workspace = true }
 cranelift-control = { workspace = true }
 wasmtime-unwinder = { workspace = true, optional = true, features = ["cranelift"] }
 anyhow = { workspace = true }
-region = "3.0.2"
+region = { git = "https://github.com/RossComputerGuy/region-rs", branch = "fix/uefi" }
 libc = { workspace = true }
 target-lexicon = { workspace = true }
 memmap2 = { version = "0.2.1", optional = true }
diff --git a/cranelift/jit/src/backend.rs b/cranelift/jit/src/backend.rs
index cbed2c3217bf..2eb430c39c71 100644
--- a/cranelift/jit/src/backend.rs
+++ b/cranelift/jit/src/backend.rs
@@ -17,6 +17,7 @@ use cranelift_module::{
 use log::info;
 use std::cell::RefCell;
 use std::collections::HashMap;
+#[cfg(not(target_os = "uefi"))]
 use std::ffi::CString;
 use std::io::Write;
 use target_lexicon::PointerWidth;
@@ -88,7 +89,13 @@ impl JITBuilder {
         libcall_names: Box<dyn Fn(ir::LibCall) -> String + Send + Sync>,
     ) -> Self {
         let symbols = HashMap::new();
+
+        #[cfg(not(target_os = "uefi"))]
         let lookup_symbols = vec![Box::new(lookup_with_dlsym) as Box<_>];
+
+        #[cfg(target_os = "uefi")]
+        let lookup_symbols = vec![];
+
         Self {
             isa,
             symbols,
@@ -656,7 +663,7 @@ impl Module for JITModule {
     }
 }
 
-#[cfg(not(windows))]
+#[cfg(all(not(windows), not(target_os = "uefi")))]
 fn lookup_with_dlsym(name: &str) -> Option<*const u8> {
     let c_str = CString::new(name).unwrap();
     let c_str_ptr = c_str.as_ptr();
diff --git a/cranelift/jit/src/memory/system.rs b/cranelift/jit/src/memory/system.rs
index bd845aef4a17..1b5f7e68cfc0 100644
--- a/cranelift/jit/src/memory/system.rs
+++ b/cranelift/jit/src/memory/system.rs
@@ -1,6 +1,10 @@
 use cranelift_module::{ModuleError, ModuleResult};
 
-#[cfg(all(not(target_os = "windows"), feature = "selinux-fix"))]
+#[cfg(all(
+    not(target_os = "windows"),
+    not(target_os = "uefi"),
+    feature = "selinux-fix"
+))]
 use memmap2::MmapMut;
 
 #[cfg(not(any(feature = "selinux-fix", windows)))]