diff --git a/static/app/constants/sdk.ts b/static/app/constants/sdk.ts
index 9fb862a35fb3..f4bf829fc30c 100644
--- a/static/app/constants/sdk.ts
+++ b/static/app/constants/sdk.ts
@@ -14,6 +14,22 @@ export const IGNORED_SPAN_NAMES = ['amplitude.com', 'pendo.io', 'reload.getsentr
 // pollute our breadcrumbs since they may occur a LOT.
 //
 // XXX(epurkhiser): Note some of these hosts may only apply to sentry.io.
+/**
+ * Deny errors originating from browser extensions. These are third-party
+ * scripts injected into Sentry pages and are not actionable by us.
+ * See: https://docs.sentry.io/platforms/javascript/configuration/filtering/#decluttering-sentry
+ */
+export const IGNORED_ERROR_DENY_URLS = [
+  // Chrome and generic extension paths (e.g. /extensions/google/setup/)
+  /extensions\//i,
+  // Chrome extension protocol
+  /^chrome-extension:\/\//i,
+  // Firefox extension protocol
+  /^moz-extension:\/\//i,
+  // Safari extension protocol
+  /^safari-extension:\/\//i,
+];
+
 export const SPA_MODE_ALLOW_URLS = [
   'localhost',
   'dev.getsentry.net',
diff --git a/static/app/serviceWorker/worker/initializeSentry.ts b/static/app/serviceWorker/worker/initializeSentry.ts
index d01abdf6b3ff..05e1790c8b2e 100644
--- a/static/app/serviceWorker/worker/initializeSentry.ts
+++ b/static/app/serviceWorker/worker/initializeSentry.ts
@@ -3,6 +3,7 @@ import type {Breadcrumb} from '@sentry/browser';
 
 import {
   IGNORED_BREADCRUMB_FETCH_HOSTS,
+  IGNORED_ERROR_DENY_URLS,
   IGNORED_SPAN_NAMES,
   SENTRY_RELEASE_VERSION,
   SPA_DSN,
@@ -36,6 +37,7 @@ export function initializeSentry({
   isInitialized = true;
   Sentry.init({
     allowUrls: SPA_DSN ? SPA_MODE_ALLOW_URLS : sentryConfig.allowUrls,
+    denyUrls: IGNORED_ERROR_DENY_URLS,
     dsn: SPA_DSN || dsn,
     release: SENTRY_RELEASE_VERSION ?? sentryConfig.release,
     environment: sentryConfig.environment,